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White Paper

Panel Discussion on Gene Sequencing and Personalized Medicine


The TCS Innovation Forum 2012 brought together thinkers, senior researchers, CXOs, COIN alliance partners from several areas (The University of Berkeley) and technology providers like Amazon to discuss new methods of gene sequencing and the technological advancements especially in field of personalized medicines, at Le Meridien, Cambridge, Massachusetts.

Host: K Ananth Krishnan, VP & CTO, TCS
Moderator: Rajgopal Srinivasan, Principal Scientist, TCS Innovation Labs - Hyderabad


  • Prof. Lior Pachter, Director, Laboratory for Mathematical and Computational Biology in the Mathematics Department, University of California, Berkeley
  • Dr. Sharmila Mande, Principal Scientist & Head – Bio Sciences R&D, TCS
  • Prof. Steven Brenner, Professor - University of California, Berkeley; Adjunct Professor - University of California at San Francisco; and Faculty Scientist - Lawrence Berkeley National Laboratory
  • Joe Baron, Solutions Architect, Amazon Web Services

Here, we present some interesting cases of personalizing medicine and big data management and surprising uses of next gen sequencing of DNA.

The panel first discussed the exponential growth in computing power and its benefits to research. Genomic research generates big data. Joe Baron of Amazon Web Services spoke of the “Genomic Cloud” and why it resonates well with researchers in life sciences. Prof. Brenner discussed, with examples, the dramatic benefits of personalized medicine made possible with individual DNA information.

Each panelist showcased research in advancing metagenomics and gene sequencing. Clinical trials, privacy and ethical issues, the challenge of making drugs, which cater to one genetic disposition and the related costs were also in focus.

Read the full panel discussion to get an insight into technology’s role in enabling metagenomic research and personalized medicine.