Applying multi-omics technology to personalize therapies
With the shift towards precision medicine, the focus of life sciences research is to capture, correlate, and connect a patient's molecular level information with diseases and treatments
Multi-omics, an approach that analyzes a combination of genomic, meta-genomic proteomic, epigenomic, phenomic, and omics data to discover new cures—is fast gaining ground. Life sciences organizations and research institutions are in the process of compiling genomic sequences and detailed molecular information of millions of people, to improve wellness and health outcomes.
TCS' Genomics Research Services enables life sciences organizations to derive actionable insights by providing sophisticated genome sequencing and analysis services enabled by its proprietary tools, algorithms, and platforms. TCS can help design and execute genomics studies that can lead to improved understanding of underlying biology, identification of new targets, and novel biomarkers which in turn lead to personalized therapies and patient stratification for clinical research or treatment selection.
Accelerating genomic interpretation in drug discovery
While significant improvements in DNA sequencing technologies help generate vast amounts of genomic data, clinical interpretation of this data, for instance, linking of DNA sequence anomalies or variations to the phenotypes and clinical conditions, is a tremendous challenge. The genome interpretation process, is encumbered by the many steps required to assemble raw sequences, perform quality assurance checks, create DNA annotations by integrating information from a multitude of sources, and prioritize variants relevant to the phenotypes of interest.
TCS’ focus is to use comprehensive data integration and analytics techniques to accelerate genomic interpretation in drug discovery and clinical research efforts, with services which ensure that genome sequencing experiments meet acceptable quality benchmarks, and data quality can be traced back to individual lab steps. TCS’ bioinformatics pipeline for the automated execution of genome as well as metagenome sequence analysis, includes a combination of open source and proprietary algorithms deployed on its in-house or client software platform.
What we offer
TCS uses its methodologies, tools, and platforms to design cutting-edge genomics research services
TCS' Genomics Research Services include:
TCS’ services support various applications such as target resequencing, transcript profiling, miRNA sequencing, and microbiome profiling (16 S rRNA sequencing), with sample processing from different samples including frozen tissue, blood, saliva, FFPE, stool, and so on.
How you benefit
TCS’ infrastructure and solutions assist in designing and conducting comprehensive genomic studies
Our studies with TCS are having profound implications in the clinic for the families of diagnosed children and influencing the use of genome analysis methods in research laboratories and clinical practice worldwide. This ground-breaking work is helping to redefine how genetic diseases and traits are diagnosed and analyzed.